Pranoprofen

Pranoprofen
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	S01BC09 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid;
CAS Number	52549-17-4 ;
PubChem CID	4888;
ChemSpider	4719 ;
UNII	2R7O1ET613;
ChEMBL	ChEMBL367463 ;
CompTox Dashboard (EPA)	DTXSID1023497 ;
ECHA InfoCard	100.207.151
Chemical and physical data
Formula	C15H13NO3
Molar mass	255.273 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O;
	InChI InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18) ; Key:TVQZAMVBTVNYLA-UHFFFAOYSA-N ;
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Pranoprofen (INN) is a nonsteroidal anti-inflammatory drug (NSAID) used in ophthalmology.^[1]

References

^ Akyol-Salman I, Leçe-Sertöz D, Baykal O (June 2007). "Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery". Journal of Ocular Pharmacology and Therapeutics. 23 (3): 280–3. doi:10.1089/jop.2006.108. PMID 17593012.

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[1] Akyol-Salman I, Leçe-Sertöz D, Baykal O (June 2007). "Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery". Journal of Ocular Pharmacology and Therapeutics. 23 (3): 280–3. doi:10.1089/jop.2006.108. PMID 17593012.

[1]

v t e Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones / pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡
salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate
acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bufexamac Bumadizone Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indometacin Indometacin farnesil Isoxepac Ketorolac Lonazolac Mofezolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†
oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Pivoxicam Tenoxicam
propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pelubiprofen Piketoprofen Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ Zaltoprofen COX-inhibiting nitric oxide donator: Naproxcinod
n-arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Floctafenine Flufenamic acid Flunixin Flutiazin Glafenine^† Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid
COX-2 inhibitors (coxibs)	Apricoxib Celecoxib (+tramadol) Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†
other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Grapiprant^‡ Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase / orgotein Tenidap
NSAID combinations	Ibuprofen/famotidine Ibuprofen/hydrocodone Ibuprofen/oxycodone Ibuprofen/paracetamol Meloxicam/bupivacaine Meloxicam/rizatriptan Naproxen/diphenhydramine Naproxen/esomeprazole
Key: underline indicates initially developed first-in-class compound of specific group; ^#WHO-Essential Medicines; ^†withdrawn drugs; ^‡veterinary use.
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Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	S01BC09 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
CAS Number	52549-17-4^N
PubChem CID	4888
ChemSpider	4719^Y
UNII	2R7O1ET613
ChEMBL	ChEMBL367463^Y
CompTox Dashboard (EPA)	DTXSID1023497
ECHA InfoCard	100.207.151
Chemical and physical data
Formula	C₁₅H₁₃NO₃
Molar mass	255.273 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O
InChI InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18)^Y Key:TVQZAMVBTVNYLA-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)