Methylallyltryptamine

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MALT
Clinical data
Other namesMALT; N,N-Methylallyltyptamine
Routes of
administration		Oral, smoking, vaping[1]
Drug classSerotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Onset of actionUnknown[1][2]
Duration of actionUnknown[1][2]
Identifiers
  • N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18N2
Molar mass214.312 g·mol−1
3D model (JSmol)
  • CN(CCC1=CNC2=CC=CC=C21)CC=C
  • InChI=1S/C14H18N2/c1-3-9-16(2)10-8-12-11-15-14-7-5-4-6-13(12)14/h3-7,11,15H,1,8-10H2,2H3
  • Key:GXCLVBGFBYZDAG-UHFFFAOYSA-N

Methylallyltryptamine (MALT), also known as N-methyl-N-allyltryptamine, is a lesser-known psychedelic drug from the tryptamine family.[1] It is a novel compound with very little history of human use.[1] It is closely related to methylpropyltryptamine (MPT).[1] The drug has been sold online as a designer drug.[1] Very little information on the pharmacology or toxicity of MALT is available.[citation needed]

Use and effects

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MALT was not included in Alexander Shulgin's 1997 book TiHKAL (Tryptamines I Have Known and Loved).[2] However, years after the book's publication, he described MALT as having important unexplored potential as a psychedelic drug.[3] Subsequently, MALT was encountered as a novel designer drug.[1] It has been reported to have been used at doses of 25 to 50 mg via routes including oral, smoking, or vaping.[1] The drug's effects have been described as comparable to those of methylpropyltryptamine (MPT) but less pronounced.[1]

Interactions

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See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

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Pharmacodynamics

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MALT is a serotonin receptor modulator and has been found to interact with the serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors.[4]

Chemistry

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Analogues

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Analogues of MALT include 4-HO-MALT, 4-AcO-MALT, 5-MeO-MALT, diallyltryptamine (DALT), methylpropyltryptamine (MPT), and methylisopropyltryptamine (MiPT), among others.

History

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MALT was first described in the scientific literature by Niels Jensen of the University of Göttingen by 2004.[4] The drug was subsequently first encountered as a novel designer drug by 2018.[1]

Society and culture

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MALT Crystals
A ziplock bag containing 100mg of MALT crystals, labeled "Not for human consumption".

MALT is not explicitly scheduled in any countries; however, it could be considered a psychoactive substance under the United Kingdom Psychoactive Substances Act, which requires the prosecutor to prove that the substance is psychoactive in order for a person to be charged with an offense.[5] It could also be considered a structural analogue of a scheduled substance under the United States Federal Analogue Act due to its similarity to scheduled tryptamines.

See also

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References

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  1. ^ a b c d e f g h i j k https://isomerdesign.com/bitnest/aipsin/13.%20Issue%2011,%20Nov%202020.pdf
  2. ^ a b c Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  3. ^ Morris H (2014). "Alexander Shulgin (1925–2014)". The Fabulist. No. 5. On that day in 2010, Alexander Shulgin was sitting outside under a parasol in his front yard surrounded by admirers, looking very happy, and talking discursively about the unexplored potential in 5-ethoxylated tryptamines and asymmetrical N-allyl-tryptamines such as MAlT, EAlT, PAlT, and iPAlT
  4. ^ a b Jensen N (2004). Tryptamines as Ligands and Modulators of the Serotonin 5‑HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens (PDF) (Thesis). Georg-August-University Göttingen. doi:10.53846/goediss-2111.
  5. ^ "Psychoactive Substances Act Guidance" (PDF). The Crown Prosecution Service. Retrieved 2021-09-23.
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