2C-T-15

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2C-T-15
Clinical data
Other names4-Cyclopropylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-cyclopropylthiophenethylamine; SESQUI
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action"Several hours"[1]
Identifiers
  • 2-[4-(cyclopropylsulfanyl)-2,5-dimethoxyphenyl]ethan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H19NO2S
Molar mass253.36 g·mol−1
3D model (JSmol)
Melting point203.5 to 204.5 °C (398.3 to 400.1 °F)
  • COc2cc(SC1CC1)c(cc2CCN)OC
  • InChI=1S/C13H19NO2S/c1-15-11-8-13(17-10-3-4-10)12(16-2)7-9(11)5-6-14/h7-8,10H,3-6,14H2,1-2H3 checkY
  • Key:HHAPMOUVSYQKLK-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

2C-T-15, also known as 4-cyclopropylthio-2,5-dimethoxyphenethylamine, is a psychedelic phenethylamine of the 2C family.[1] It was presumably first synthesized by Alexander Shulgin and reported in his book PiHKAL (Phenethylamines i Have Known And Loved).[1]

Use and effects

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The dose range of 2C-T-15 is typically 30 mg or more. Its duration is unspecified by Shulgin, and its entry in PiHKAL says it lasts for "several hours."[1] The effects are not prominent, and 2C-T-15 is not very potent.

Toxicity

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The toxicity of 2C-T-15 is not well documented. 2C-T-15 is much less potent than 2C-T-7, but it may be expected that at very high doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.[citation needed]

Interactions

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See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

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Pharmacodynamics

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The mechanism that produces 2C-T-15's hallucinogenic and entheogenic effects has not been specifically established; however, it is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.[citation needed]

Chemistry

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2C-T-15 is the 2 carbon homologue of Aleph-15, which has not been synthesized.[1] The full chemical name is 2-[4-(2-cyclopropylthio)-2,5-dimethoxyphenyl]ethanamine.[1] The drug has structural properties similar to 2C-T-2 and other drugs in the 2C-T series.[1]

History

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2C-T-15 was first described in the scientific literature by Alexander Shulgin and colleagues in 1991.[2]

Society and culture

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Canada

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As of October 31, 2016, 2C-T-15 is a controlled substance (Schedule III) in Canada.[3]

United Kingdom

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2C-T-15 is a class A drug in the UK under the Misuse of Drugs act.

United States

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2C-T-15 is not explicitly illegal in the USA, but possession and sales of 2C-T-15 could be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7.

See also

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References

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  1. ^ a b c d e f g h Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628.
  2. ^ Shulgin AT, Shulgin A, Jacob P (January 1991). "Central nervous system (CNS) activity of two new psychoactive compounds". Journal of Psychoactive Drugs. 23 (1): 95–96. doi:10.1080/02791072.1991.10472583. eISSN 2159-9777. PMID 1941371. Archived from the original on 2025-07-13.
  3. ^ "Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.
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