Draft:Zhongping Chen
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Comment: Several sections have been copied from optica.org and the article contains an uncited paragraph GGOTCC 17:37, 7 September 2025 (UTC)
Zhongping Chen | |
|---|---|
 | |
| Citizenship | American |
| Alma mater | Shanghai Jiao Tong University; Cornell University |
| Known for | Optical Coherence Tomography, Doppler Optical Coherence Tomography |
| Scientific career | |
| Fields | Biomedical engineering, Optical engineering |
| Institutions | University of California, Irvine; Beckman Laser Institute |
| Thesis | Nonlinear optical properties of bacteriorhodopsin and retinal chromophores and their applications for optical information storage and processing (1993) |
| Doctoral advisor | Aaron Lewis |
Zhongping Chen
[edit]Zhongping Chen is a Professor of Biomedical Engineering and Director of the F-OCT Laboratory at the University of California, Irvine.[1] He is a co-founder and chairman of the board of directors of OCT Medical Imaging, Inc.
Education and Career
[edit]Dr. Chen received his B.S. degree from Shanghai Jiao Tong University and his M.S. and Ph.D. degrees from Cornell University. At UCI, he leads the Functional Optical Coherence Tomography Laboratory (F-OCT)[2], focusing on translational technologies for medical imaging and diagnosis.
Research Contributions
[edit]Zhongping Chen is a biomedical engineer and a professor at the University of California, Irvine, recognized for his contributions to biophotonics and biomedical optics.[1] His fundamental work has expanded optical coherence tomography (OCT) from purely structural imaging into a platform for functional imaging, significantly impacting both scientific research and clinical medicine. Chen was among the first to develop Doppler OCT (D-OCT), a technology for visualizing and quantifying blood flow in microcirculation.[3] [4] [5] His group played a leading role in the subsequent development of OCT angiography (OCTA), which is widely used in ophthalmology for diagnosing retinal diseases. His research also encompasses the development of optical coherence elastography (OCE) and second harmonic OCT. [6] [7]
A key aspect of Chen's work is the translation of imaging technologies into clinical practice. His laboratory designed early miniaturized endoscopic and intravascular probes for OCT and fiber-based multiphoton microscopy, enabling high-resolution internal imaging. This led to the development of an integrated intravascular OCT/ultrasound (US) system, demonstrating the first co-registered imaging with a single probe.[8] His group also developed a long-range OCT system for airway imaging in pediatric obstructive sleep apnea. These innovations have been applied to diagnose diseases in cardiology, oncology, airway management, ophthalmology, and the brain. [9] Chen has authored more than 400 peer-reviewed publications and holds over 25 patents in the fields of biomaterials, biosensors, and biomedical imaging.[10]
Awards and Honors
[edit]- Fellow, Optica (formerly Optical Society of America), 2007.[11]
- Fellow, SPIE (International Society for Optics and Photonics).[12]
- Fellow, American Institute of Medical and Biological Engineering (AIMBE), 2005. [13]
- Michael S. Feld Biophotonics Award, 2024.[14]
References
[edit]- ^ a b "Zhongping Chen – UCI Engineering Profile". University of California, Irvine. Retrieved 2025-08-28.
- ^ "Functional OCT Laboratory (F-OCT)". University of California, Irvine. Retrieved 2025-08-28.
- ^ Chen, Z.; Milner, T. E.; Srinivas, S.; Wang, X.; Malekafzali, A.; van Gemert, M. J.; Nelson, J. S. (1997). "Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography". Optics Letters. 22 (14): 1119–1121. Bibcode:1997OptL...22.1119C. doi:10.1364/OL.22.001119. PMID 18185770.
- ^ Chen, Z.; Milner, T. E.; Dave, D.; Nelson, J. S. (1997). "Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media". Optics Letters. 22 (1): 64–66. Bibcode:1997OptL...22...64C. doi:10.1364/OL.22.000064. PMID 18183104.
- ^ Zhao, Y.; Chen, Z.; Saxer, C.; Xiang, S.; de Boer, J. F.; Nelson, J. S. (2000). "Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity". Optics Letters. 25 (2): 114–116. Bibcode:2000OptL...25..114Z. doi:10.1364/OL.25.000114. PMID 18059800.
- ^ Qi, W.; Chen, R.; Chou, L.; Liu, G.; Zhang, J.; Zhou, Q.; Chen, Z. (2012). "Phase-resolved acoustic radiation force optical coherence elastography". Journal of Biomedical Optics. 17 (11): 110505. Bibcode:2012JBO....17k0505Q. doi:10.1117/1.JBO.17.11.110505. PMC 3487536. PMID 23123971.
{{cite journal}}: CS1 maint: article number as page number (link) - ^ Li, R.; Hua, Y.; Zhang, F.; Qian, X.; Gong, C.; Wan, X.; Zhou, Q. (2025). "Multiscale analysis of equatorial sclera anisotropy: Revealing discrepancies in fiber orientation and mechanical properties". Science Advances. 11 (28): eadp8631. Bibcode:2025SciA...11P8631L. doi:10.1126/sciadv.adp8631. PMC 12239965. PMID 40632852.
{{cite journal}}: CS1 maint: article number as page number (link) - ^ Yin, J.; Li, X.; Jing, J.; Li, J.; Mukai, D.; Mahon, S.; Chen, Z. (2011). "Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging". Journal of Biomedical Optics. 16 (6): 060505–060505–3. Bibcode:2011JBO....16f0505Y. doi:10.1117/1.3589097. PMC 3124531. PMID 21721799.
- ^ Wang, J.; Ye, Q.; Chou, L.; Qiu, S.; Xu, X.; Chen, Z. (2024). "Miniaturized head-mount Doppler optical coherence tomography scope for freely moving mouse". ACS Photonics. 11 (8): 3381–3389. doi:10.1021/acsphotonics.4c00702. PMC 11342407. PMID 39184188.
- ^ "Zhongping Chen – Google Scholar". Google Scholar. Retrieved 2025-08-28.
- ^ "2007 Optica Fellows". Optica. Retrieved 2025-08-28.
- ^ "Zhongping Chen – SPIE Profile". SPIE (International Society for Optics and Photonics). Retrieved 2025-09-10.
- ^ "Zhongping Chen – AIMBE College of Fellows". American Institute for Medical and Biological Engineering (AIMBE). AIMBE. Retrieved 2025-09-10.
- ^ "2024 Michael S. Feld Biophotonics Award Winner". Optica. 2024. Retrieved 2025-08-28.