Peptostreptococcus stomatis
| Peptostreptococcus stomatis | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Bacillota |
| Class: | Clostridia |
| Order: | Peptostreptococcales |
| Family: | Peptostreptococcaceae |
| Genus: | Peptostreptococcus |
| Species: | P. stomatis
|
| Binomial name | |
| Peptostreptococcus stomatis Downes and Wade 2006[1]
| |
Peptostreptococcus stomatis is a bacterium from the family Peptostreptococcaceae. It is a commensal bacterium and was first isolated from the human oral cavity in 2006, however it can also invade other areas of the body and cause infection, particularly in those with weakened immune systems.[2]
Biology and ecology
[edit]P. stomatis cells are gram positive and cocci in shape. They are catalase-negative as they do not have the enzyme catalase, which protects catalase-positive bacteria from hydrogen peroxide by converting it into hydrogen and oxygen. P. stomatis cells are 0.8 × 0.8 – 0.9 μm, and are arranged in pairs and short chains. P. stomatis colonies are circular and 0.8 – 1.8 mm in diameter.[2] P. stomatis cells are anaerobic and spore forming. They are normally found in the oral cavity as part of the oral microbiome, although this bacterium has been found alive in mouse stools, which shows that it can also survive the harsh conditions within the gastrointestinal tract.[3]
P. stomatis produces acetic, butyric, isobutyric, isovaleric and isocaproic acids from fermentation. It is weakly saccharolytic, and can weakly ferment fructose, glucose and maltose. It grows moderately in broth media, and growth can be improved by adding fermentable carbohydrates.[2]
References
[edit]- ^ Page Species: Peptostreptococcus stomatis on "LPSN - List of Prokaryotic names with Standing in Nomenclature". Deutsche Sammlung von Mikroorganismen und Zellkulturen. Retrieved 2022-11-09.
- ^ a b c Downes, Julia; Wade, William G. (2006). "Peptostreptococcus stomatis sp. nov., isolated from the human oral cavity". International Journal of Systematic and Evolutionary Microbiology. 56 (4): 751–754. doi:10.1099/ijs.0.64041-0. ISSN 1466-5034.
- ^ Huang, Pingmei; Ji, Fenfen; Cheung, Alvin Ho-Kwan; Fu, Kaili; Zhou, Qiming; Ding, Xiao; Chen, Danyu; Lin, Yufeng; Wang, Luyao; Jiao, Ying; Chu, Eagle S. H.; Kang, Wei; To, Ka Fai; Yu, Jun; Wong, Chi Chun (2024-08-14). "Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK". Cell Host & Microbe. 32 (8): 1365–1379.e10. doi:10.1016/j.chom.2024.07.001. ISSN 1931-3128. PMID 39059397.
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