Draft:Sandrine Thuret


Sandrine Thuret
Dr. rer nat., FHEA
Born
Burgundy, France
NationalityFrench
Alma materPolytechnic Institute of Clermont-Auvergne; Claude Bernard University Lyon 1; Heidelberg University
Known forAdult hippocampal neurogenesis; Diet and mental health; Cognitive ageing
SpouseRobert Hindges
AwardsUK Research Council Academic Research Award (2007); Eppendorf & Science Prize for Neurobiology (2020)
Scientific career
FieldsNeuroscience; Neurogenesis; Stem cell biology; Mental health
InstitutionsKing’s College London
Websitehttps://www.thuretlab.com

Sandrine Thuret (Dr. rer nat., FHEA) is a French neuroscientist and entrepreneur, born in Burgundy, France. She is known for her research on adult hippocampal neurogenesis and its regulation by diet, lifestyle, and metabolic factors, and its impact on cognition, mood, and ageing. She is Professor of Neuroscience at King’s College London and co-head of the Department of Basic & Clinical Neuroscience at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN). She directs the Neurogenesis & Mental Health Laboratory, co-directs the King’s Human and Synthetic Minds Institute, and oversees multiple postgraduate programs in biomedical and mental health research. Thuret is also the founder of the spinout company NeuroPrognostix and a science communicator, delivering the TED Talk "You can grow new brain cells. Here’s how," which has been viewed over 14 million times.

Early life and education

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Thuret was born and raised in Burgundy, France. She earned a Master’s degree in Bio-engineering from the Polytechnic Institute of Clermont-Auvergne (1994–1997), followed by a Master’s degree in Ageing Biology at Claude Bernard University Lyon 1 (1997–1998). She obtained her PhD in Neuroscience from Heidelberg University in 2002, studying the development of dopaminergic neurons in the central nervous system.[1]

She completed her postdoctoral research at the Salk Institute for Biological Studies under Fred Gage, investigating neural stem cells and adult hippocampal neurogenesis.

Academic career

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Thuret established her independent laboratory at King’s College London in 2007 after receiving the UK Research Council Academic Research Award. She became a lecturer in 2011 and later Professor of Neuroscience. She co-heads the Department of Basic & Clinical Neuroscience at IoPPN, leads the Neurogenesis & Mental Health Laboratory, and co-directs the King’s Human and Synthetic Minds Institute. She also oversees the Wellcome-funded PhD Programme in Mental Health Research for Health Professionals and the UKRI MRC Doctoral Training Partnership in Biomedical Sciences.

Thuret is an advocate for gender equality and diversity in academia, serving as her faculty’s Gender Equality Champion for five years and participating in the IoPPN Culture, Equality, Diversity & Inclusion Committee. She serves as an academic advisor to the International Life Sciences Institute (ILSI) on Nutrition and Brain Health and is an editor for Nutrition and Healthy Aging.

Research

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Thuret’s laboratory studies adult hippocampal neurogenesis (AHN), focusing on how new neurons are generated in the adult brain and how they affect cognition, mood, and mental health. Her research integrates bioengineering, molecular and cellular biology, behavioral neuroscience, and translational human studies.

Key research areas include:

  • Diet and metabolism: Investigating the effects of nutrients, intermittent fasting, and caloric restriction on AHN.[2]
  • Ageing and cognitive resilience: Studying lifestyle interventions to enhance brain plasticity in ageing.
  • Depression and mental health: Linking human hippocampal progenitor assays with metabolic biomarkers to study depressive symptoms.[3]
  • Neurodegeneration and Alzheimer’s disease: Leading international consortia to translate neurogenesis research into understanding cognitive ageing and neurodegenerative disorders.

Her work has been cited over 7,000 times.

Entrepreneurship

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Thuret founded NeuroPrognostix, a spinout company developing neurogenesis-based blood tests for early detection and monitoring of neurological and psychiatric conditions. The company participated in King’s Spinout Accelerator Cohort II.[4]

Public engagement

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Thuret delivered the TED Talk "You can grow new brain cells. Here’s how" in 2015, which has been viewed over 14 million times and translated into 38 languages.[5] She is also an editor for BrainFacts.org.

Awards and honours

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  • UK Research Council Academic Research Award (2007)
  • Fellow of the Higher Education Academy (FHEA)
  • IoPPN Awards 2025 – Collaborative Research Excellence Award, Research Guidance and Mentorship Award, and Research Impact Award.[6]

References

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  1. ^ "Sandrine Thuret – Research Portal". King’s College London. Retrieved 2 September 2025.
  2. ^ Stangl, D.; Thuret, S. (2009). "Impact of diet on adult hippocampal neurogenesis". Genes & Nutrition. 4 (4): 271–282. doi:10.1007/s12263-009-0134-5. PMC 2771079. PMID 19789765.
  3. ^ Du Preez, A.; Lefèvre‑Arbogast, S.; González-Domínguez, R.; Thuret, S. (2022). "Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study". Molecular Psychiatry. 27 (9): 3425–3440. doi:10.1038/s41380-022-01697-2. PMC 9493004. PMID 35668640.
  4. ^ "Meet the Spinouts on King's Spinout Accelerator Cohort II". King’s College London. 2025-06-19. Retrieved 2 September 2025.
  5. ^ "Sandrine Thuret: You can grow new brain cells. Here's how". TED. 2015-06-01. Retrieved 2 September 2025.
  6. ^ "Celebrating our staff at the IoPPN Awards 2025". King’s College London. 2025-08-15. Retrieved 2 September 2025.
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See also

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