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Saeed Balalaie | |
|---|---|
| Born | September 26, 1965 Rasht, Gilan Province, Iran |
| Nationality | Iranian |
| Alma mater |
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| Known for | |
| Awards |
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| Scientific career | |
| Fields | Organic chemistry, Peptide synthesis, Multicomponent reaction |
| Institutions | K. N. Toosi University of Technology |
| Doctoral advisor | Mohammad Mahmoudi Hashemi |
Saeed Balalaie (Persian: سعید بلالایی; born 26 September 1965) is an Iranian organic chemist and professor at K. N. Toosi University of Technology. His research focuses on multicomponent reactions, peptide synthesis, and the synthesis of active pharmaceutical ingredients.[1]
Balalaie was a recipient of the 33rd Khwarizmi International Award in 2019 (announced in February 2020) for applied research[2][3] and was named Iran's National Outstanding Researcher in the same year (2019).[2] He has received multiple research fellowships from the Alexander von Humboldt Foundation and served as the foundation's Scientific Ambassador in Iran from 2015 to 2020.[4]
Early life and education
[edit]Balalaie was born on 26 September 1965 in Rasht, Gilan Province, Iran.[1] He completed his undergraduate studies in Chemistry at the University of Tehran (1984–1989), followed by a Master of Science degree in Organic Chemistry from Shahid Beheshti University (1989–1991).[1]
He earned his Ph.D. in Organic Chemistry from Sharif University of Technology (1992–1996), where he worked on "Photooxygenation of organic compounds by singlet oxygen" under the supervision of Professor Mohammad Mahmoudi Hashemi. During his doctoral studies, he spent six months as a visiting researcher in Germany working with Professor Junes Ipaktschi.[1]
Career
[edit]Balalaie joined the faculty of K. N. Toosi University of Technology as an Assistant Professor (1997-2003), was promoted to Associate Professor (2003-2007), and has served as a Full Professor since 2007.[1]
Throughout his career, he has maintained research collaborations with German institutions through multiple Alexander von Humboldt Foundation fellowships, beginning in 2002. His collaborations include work at Heidelberg University, University of Freiburg, Heinrich Heine University Düsseldorf, and the University of Duisburg-Essen.[4] From 2015 to 2020, he served as the Scientific Ambassador of the Alexander von Humboldt Foundation in Iran, facilitating scientific cooperation between Iranian and German researchers.[4][1]
Research contributions
[edit]Balalaie's research focuses on several areas of organic chemistry, including environmentally friendly synthetic methods and pharmaceutical applications.[5]
Multicomponent reactions
[edit]His research group has worked on the development of multicomponent reactions (MCRs), particularly for the synthesis of heterocyclic compounds. His work in this area has included the use of zeolite catalysts for the preparation of tetrasubstituted imidazoles and other heterocycles.[6]
Active pharmaceutical ingredients
[edit]His research has also involved developing synthetic routes for several active pharmaceutical ingredients (APIs).[5] Compounds published by his group include:
Peptide synthesis
[edit]In peptide synthesis, Balalaie's work has included the synthesis of therapeutic peptides such as triptorelin, leuprolide, octreotide, and oxytocin.[5] His group has also designed cyclopeptides containing heterocyclic structures (imidazole, thiazole, oxazole) intended to serve as potential anticancer agents.[5] His book "Peptide Chemistry in Persian" was recognized as a winner of the Iran Book of the Year Award in 1399 (2020).[7]
Awards and honors
[edit]- National Outstanding Researcher Award (2019)[2]
- First Prize in Applied Research Projects, 33rd Khwarizmi International Award (2019)[2][3]
- Iran Book of the Year Award (2020), for "Peptide Chemistry in Persian"[7]
- Distinguished University Professor in Iran, Ministry of Science, Research and Technology (2021)[1]
- Distinguished Organic Chemistry Professor in Iran, by Iranian Chemical Society (2013)[1]
- Alexander von Humboldt Foundation Research Fellowship: Awarded multiple research stays (2002, 2004, 2007, 2011, 2014, 2017)[4][1]
- Scientific Ambassador of the Alexander von Humboldt Foundation in Iran (2015–2020)[4]
- Outstanding Researcher Award, K.N. Toosi University of Technology (multiple years)[1]
Selected publications
[edit]- Balalaie, S.; Hashtroudi, M. S.; Arabanian, A. (2000). "One-pot synthesis of tetrasubstituted imidazoles catalyzed by zeolite HY and silica gel under microwave irradiation". Green Chemistry. 2 (6): 274–276. doi:10.1039/b006201o.
- Balalaie, S.; Bararjanian, M.; Amani, A. M.; Movassagh, B. (2006). "(S)-Proline as a neutral and efficient catalyst for the one-pot synthesis of tetrahydrobenzo [b] pyran derivatives in aqueous media". Synlett. 2006 (2): 263–266. doi:10.1055/s-2005-923606.
- Bararjanian, M.; Balalaie, S.; Rominger, F.; Movassagh, B.; Bijanzadeh, H. R. (2010). "Six-component reactions for the stereoselective synthesis of 3-arylidene-2-oxindoles via sequential one-pot Ugi/Heck carbocyclization/Sonogashira/nucleophilic addition". The Journal of Organic Chemistry. 75 (9): 2806–2812. doi:10.1021/jo902713x. PMID 20387848.
- Balalaie, S.; Bararjanian, M.; Hosseini, M.S.; Bigdeli, Z. (2006). "One-pot synthesis of 1,4-dihydropyridine derivatives in a solvent-free condition". Helvetica Chimica Acta. 89 (8): 1769–1773. doi:10.1002/hlca.200690161.
- Balalaie, S.; Sharafi-Kolkesh, A. (2003). "A novel and efficient one-pot synthesis of 2,4,6-triarylpyridines under solvent-free conditions". Zeitschrift für Naturforschung B. 58 (10): 1075–1077. doi:10.1515/znb-2003-1021.
References
[edit]- ^ a b c d e f g h i j "Saeed Balalaie - Curriculum Vitae". K.N. Toosi University of Technology. Retrieved 6 November 2025.
- ^ a b c d "Dr. Balalaie won the first rank of applied research at the Khwarizmi Festival and National Outstanding Researcher" (in Persian). Iranian Chemical Society. Retrieved 6 November 2025.
- ^ a b "Honoring the winners of the 33rd Khwarizmi International Festival" (in Persian). Islamic Republic News Agency (IRNA). 17 February 2020. Archived from the original on 2020-02-18. Retrieved 6 November 2025.
- ^ a b c d e "Prof. Dr. Saeed Balalaie". Alexander von Humboldt Foundation. Retrieved 5 November 2025.
- ^ a b c d "Saeed Balalaie Research Group". K.N. Toosi University of Technology. Retrieved 6 November 2025.
- ^ Balalaie, S.; Hashtroudi, M. S.; Arabanian, A. (2000). "One-pot synthesis of tetrasubstituted imidazoles catalyzed by zeolite HY and silica gel under microwave irradiation". Green Chemistry. 2 (6): 274–276. doi:10.1039/b006201o.
- ^ a b "Dr. Saeed Balalaie selected as the winner of the Book of the Year Award 99" (in Persian). K.N. Toosi University of Technology - Faculty of Electrical Engineering. Retrieved 6 November 2025.
External links
[edit]- Official website
- Google Scholar profile
- Faculty page at K.N. Toosi University
- Humboldt Foundation profile
Category:Living people Category:1965 births Category:Iranian chemists Category:Organic chemists Category:University of Tehran alumni Category:Shahid Beheshti University alumni Category:Sharif University of Technology alumni Category:Alexander von Humboldt Fellows Category:Khwarizmi International Award recipients