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The following locomotives are a line of diesel-electric locomotives produced by GE, starting in 2005. They are designed to meet the US EPA's Tier-2 emission standards, which took effect in 2005. They succeeded the 9-44CW and AC4400CW in 2005. Every model has enlarged radiators to accommodate the GEVO'S air-to-air intercoolers. As with the AC6000CW, the radiators project beyond the end of the hood.

Like the former C40-9W, it was delivered exclusively for Norfolk Southern, which preferred a lower horsepower rating. Soon, power demands made the railroad make a mandatory repowering to their ES44DC power ratings.

It succeeded the C44-9W in GE's line. The radiators were enlarged, it had GEVO's air-to-air cooling, and the old, 7FDL-16 was replaced by the new GEVO-12. These locomotives have been ordered by three Class I railroad in North America: BNSF Railway, CSX Transportation, and Canadian National Railway.

• ES: Evolution series
• 44: 4,400 hp (3,300 kW)
• DC: Direct current Traction motors

Pilbara Iron in Australia ordered an lengthened, international version of the ES44DC, the ES44DCi. The ES44DCi is essentially in a GE AC6000CW's body, with the radiator protruding at the back. The ES44DCi did the same. The extra length is used for the larger radiators to increase cooling capacity in the Australian outback.

The same as the ES44DCi, but with Alternating current Traction motors. Roy Hill and Rio tinto group ordered these.

It succeeded the AC4400CW in GE's line. The radiators were enlarged, it had GEVO's air-to-air cooling, and the old, 7FDL-16 was replaced by the new GEVO-12. These locomotives have been ordered by every Class I railroad in North America: Union Pacific Railroad (who refers to these locomotives as the C45ACCTE), BNSF Railway, CSX Transportation, Norfolk Southern Railway, Ferromex, CPKC Railway, and Canadian National Railway.

• ES: Evolution series
• 44: 4,400 hp (3,300 kW)
• AC: Alternating current Traction motors

It is essentially an ES44AC, but with 4 traction motors instead of the usual six. The middle axle is unpowered, this gave an A1A-A1A arrangement. No DC version was built.

• ES: Evolution series
• 44: 4,400 hp (3,300 kW)
• C4: C: indicates that it is a C-type three axle trucks, 4 indicates that there is four traction motors, Alternating current Traction motors