Draft:Ansa Biotechnologies
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| Submission declined on 12 September 2025 by Carolina2k22 (talk). This submission appears to read more like an advertisement than an entry in an encyclopedia. Encyclopedia articles need to be written from a neutral point of view, and should refer to a range of independent, reliable, published sources, not just to materials produced by the creator of the subject being discussed. This is important so that the article can meet Wikipedia's verifiability policy and the notability of the subject can be established. If you still feel that this subject is worthy of inclusion in Wikipedia, please rewrite your submission to comply with these policies.
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| Submission declined on 9 September 2025 by WeirdNAnnoyed (talk). This draft's references do not show that the subject qualifies for a Wikipedia article. In summary, the draft needs multiple published sources that are:
This submission appears to read more like an advertisement than an entry in an encyclopedia. Encyclopedia articles need to be written from a neutral point of view, and should refer to a range of independent, reliable, published sources, not just to materials produced by the creator of the subject being discussed. This is important so that the article can meet Wikipedia's verifiability policy and the notability of the subject can be established. If you still feel that this subject is worthy of inclusion in Wikipedia, please rewrite your submission to comply with these policies. Declined by WeirdNAnnoyed 18 days ago. | |
| Company type | Private |
|---|---|
| Industry | Biotechnology, Synthetic biology |
| Founded | 2018 |
| Founders | Dan Lin-Arlow, Sebastian Palluk |
| Headquarters | Emeryville, California , United States |
Key people | Jason T. Gammack (CEO) Dan Lin-Arlow (CSO) Sebastian Palluk (CTO) |
| Website | ansabio |
Ansa Biotechnologies is an American biotechnology company based in Emeryville, California. The company develops enzymatic DNA synthesis methods designed to generate long and complex synthetic DNA sequences. Nature described Ansa’s approach as a significant new method in DNA manufacturing,[1] and both GEN and The Scientist have discussed the company’s technology in the context of broader advances in synthetic biology.[2][3]
Background
[edit]Ansa Biotechnologies was founded in 2018 by Dan Lin-Arlow and Sebastian Palluk following research at the University of California, Berkeley.[3] In 2024, GenomeWeb reported the appointment of Jason T. Gammack as chief executive officer, with Lin-Arlow becoming chief scientific officer.[4]
Research and Technology
[edit]Ansa’s work centers on enzymatic DNA synthesis using terminal deoxynucleotidyl transferase (TdT) conjugated with nucleotide triphosphates, an alternative to phosphoramidite chemistry.[1] The Scientist reported that the platform achieved a 99.9% stepwise yield for a 1,005-base construct and enabled parallel synthesis of hundreds of oligonucleotides.[3] A study published in Frontiers in Bioengineering and Biotechnology documented the de novo synthesis of a 1,005-base oligonucleotide using the system.[5] A 2023 review article also cited Ansa’s approach as part of efforts to close the “gene writing gap” in synthetic biology.[6]
Applications
[edit]Coverage in GEN noted that Ansa began offering early access to long synthetic DNA constructs up to 50 kilobases in 2025.[2] Independent reporting has discussed the potential applications of such constructs in genomics and synthetic biology research.[1]
Collaborations
[edit]In 2020, Ansa partnered with TeselaGen to explore DNA design and automation workflows.[7]
References
[edit]- ^ a b c Seydel, Caroline (July 22, 2025). "Made-to-order DNA goes big: new tech doubles size of custom genetic sequences". Nature. 643 (8073): 1146–1147. Bibcode:2025Natur.643.1146S. doi:10.1038/d41586-025-02261-y. PMID 40696021.
- ^ a b "Ansa Biotechnologies rolls out early access program for long, complex synthetic DNA orders". GEN. February 10, 2025.
- ^ a b c "Enzymatic DNA synthesis: Going to great lengths". The Scientist. June 13, 2024.
- ^ "People News: Ansa Biotechnologies' Jason Gammack, Dan Lin-Arlow". GenomeWeb. March 18, 2024.
- ^ "Enzymatic DNA synthesis: demonstration of a 1,005-base oligonucleotide". Frontiers in Bioengineering and Biotechnology. August 22, 2023. doi:10.3389/fbioe.2023.1208784. PMID 37476479.
- ^ Hoose, A.; Vellacott, R.; Storch, M.; Freemont, P. S.; Ryadnov, M. G. (January 10, 2023). "DNA synthesis technologies to close the gene writing gap". PMC. 7 (3): 144–161. doi:10.1038/s41570-022-00456-9. PMC 9869848. PMID 36714378.
- ^ "TeselaGen partners with Ansa Biotechnologies on DNA automation". TeselaGen. June 15, 2020.
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