Critical Assessment of Genome Interpretation

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Overview of CAGI Competition

The Critical Assessment of Genome Interpretation (CAGI) is an annual bioinformatics competition focused on interpretation of genome variation.[1] CAGI experiments are modeled on the protocols developed in the Critical Assessment of Structure Prediction (CASP) program, adapted to the genomics domain. Over a period of a decade CAGI has conducted five rounds of challenges, attracting 738 submissions from around the world.[2] The results of which have been published in the journal Human Mutation.[3]

References

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  1. ^ "Collaboration through competition". Nature Methods (editorial). 11 (7): 695. July 2014. doi:10.1038/nmeth.3026. PMID 25110777.
  2. ^ Jain, Shantanu; Bakolitsa, Constantina; Brenner, Steven E.; Radivojac, Predrag; Moult, John; Repo, Susanna; Hoskins, Roger A.; Andreoletti, Gaia; Barsky, Daniel; Chellapan, Ajithavalli; Chu, Hoyin; Dabbiru, Navya; Kollipara, Naveen K.; Ly, Melissa; Neumann, Andrew J. (2024-02-22). "CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods". Genome Biology. 25 (1): 53. doi:10.1186/s13059-023-03113-6. ISSN 1474-760X. PMC 10882881. PMID 38389099.
  3. ^ Andreoletti, Gaia; Pal, Lipika R.; Moult, John; Brenner, Steven E. (2019). "Reports from the fifth edition of CAGI: The Critical Assessment of Genome Interpretation". Human Mutation. 40 (9): 1197–1201. doi:10.1002/humu.23876. ISSN 1098-1004. PMC 7329230. PMID 31334884.
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